Mixed Microtubules Steer Dynein-Driven Cargo Transport into Dendrites
نویسندگان
چکیده
منابع مشابه
Mixed Microtubules Steer Dynein-Driven Cargo Transport into Dendrites
BACKGROUND To establish and maintain their polarized morphology, neurons employ active transport driven by molecular motors to sort cargo between axons and dendrites. However, the basic traffic rules governing polarized transport on neuronal microtubule arrays are unclear. RESULTS Here we show that the microtubule minus-end-directed motor dynein is required for the polarized targeting of dend...
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ژورنال
عنوان ژورنال: Current Biology
سال: 2010
ISSN: 0960-9822
DOI: 10.1016/j.cub.2009.12.052